60S Ribosome: Key Component of Protein Generation in Cells (P16328)

Target Name: 60S Ribosome

NCBI ID: P16328

60S Ribosome

Other Name(s): Large subunit | Large (60S) subunit | 60S subunit

60S Ribosome: Key Component of Protein Generation in Cells

The 60S ribosome, also known as the large subunit, is a key component of the machinery that generates proteins in the cell. It is a complex protein complex that includes a small subunit (23S rRNA) and a large subunit (5S rRNA). 60S ribosome is responsible for reading the genetic code in mRNA and translating it into a specific protein sequence.

The 60S ribosome is a protein that is expressed in all eukaryotic cells and is involved in the production of a wide variety of proteins. It is one of the most well-studied protein structures in the cell and is the focus of much research in the field of molecular biology.

One of the key features of the 60S ribosome is its structure. It consists of a complex arrangement of subunits that are held together by various non-covalent interactions. The 60S ribosome is composed of the following subunits:

* 23S rRNA: This is the largest subunit of the 60S ribosome and is responsible for carrying the genetic information from the mRNA to the ribosome. It has a length of approximately 7.5 nanometers and consists of a large alpha helix and a number of smaller beta- helices.
* 5S rRNA: This is the smallest subunit of the 60S ribosome and is responsible for forming the base pairing with the tRNA. It has a length of approximately 18 nanometers and consists of a single alpha helix.
* 2mRRNA: This is a modified form of the 23S rRNA that is held in position by the 5S rRNA. It is involved in the initiation of the translation process and has been shown to play a role in the regulation of protein synthesis.
* 5.8S rRNA: This is a modified form of the 5S rRNA that is held in position by the 2mRRNA. It is involved in the regulation of protein synthesis and has been shown to play a role in the development and progression of cancer.
* 18S rRNA: This is the largest subunit of the 60S ribosome and is responsible for carrying the genetic information from the mRNA to the ribosome. It has a length of approximately 18.5 nanometers and consists of a large alpha helix and a number of smaller beta- helices.
* 23S rRNA: This is the smallest subunit of the 60S ribosome and is responsible for carrying the genetic information from the mRNA to the ribosome. It has a length of approximately 18.5 nanometers and consists of a single alpha helix.

The 60S ribosome is responsible for translating the genetic code in mRNA into a specific protein sequence. This process is highly regulated and is controlled by a number of different factors, including the concentration of various amino acids in the cell and the presence of tRNA and rRNA.

One of the key functions of the 60S ribosome is its ability to recognize and bind to specific mRNAs. This is accomplished through a process called initiation of translation, which involves the interaction between the 23S rRNA and the mRNA. Once the mRNA is bound to the 60S ribosome, the ribosome begins to read the genetic code in the mRNA and initiate the translation process.

The 60S ribosome is also involved in the regulation of protein synthesis and has been shown to play a

Protein Name: 60S Ribosome

The "60S Ribosome Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about 60S Ribosome comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets